Cardiopulmonary bypass temperature and brain function

Cardiopulmonary Bypass Temperature

Study objective: To determine if temperature during cardiopulmonary bypass (CPB) has an effect on peri¬ operative and postoperative thyroid function. Design: Prospective study comparing thyroid function duringand afterhypothermicandnormothermic CPB. Setting: Cardiac surgical unit at a university-affiliated hospital. Patients: Twelve patients scheduled to undergo car¬ diac operations with normot...

Temperature inaccuracies during cardiopulmonary bypass.

Cerebral hyperthermia caused by perfusate temperature greater than 37 degrees C during the rewarming phase of CPB has been linked to postoperative neurologic deficits. The purpose of this study was to determine the accuracy of the coupled temperature measurement system and the CDI 500 arterial temperature sensor. Seventeen patients undergoing CPB were divided into four groups, each with a diffe...

Post Cardiopulmonary Bypass Changes in Liver Function

This study examines abnormal LFT (mainly bilirubin) on postoperative day three as a predictor of open cardiac surgery mortality.1 Preoperative hyperbilirubinemia, high right atrial pressure, number of heart valves replaced and high blood transfusion requirements are risk factors predicting postoperative hyperbilirubinemia in 81% of all patients.2 This study strictly excluded high-risk condition...

The platelet function defect of cardiopulmonary bypass.

The use of cardiopulmonary bypass (CPB) during cardiac surgery is associated with a hemostatic defect, the hallmark of which is a markedly prolonged bleeding time. However, the nature of the putative platelet function defect is controversial. In this study, blood was analyzed at 10 time points before, during, and after CPB. We used a whole-blood flow cytometric assay to study platelet surface g...

Platelet function defects related to cardiopulmonary bypass.